BGC > Buscar Producto > Wnt agonist | 853220-52-7

Molecular Formula: C19H18N4O3
Molecular Weight: 350.37122
Hazard Symbols: Xi
WGKGermany: 3

Description:
BML-284 is potent, selective and cell-permeable Wnt signaling activator. It induces β-catenin and transcription factor (TCF)-dependent transcriptional activity in 293T cells in a dose dependent manner with an EC50 of 0.7 mM in vitro.

• Molecular Weight:350.37
• Boiling Point:623.4±65.0 °C at 760 mmHg
• Purity:>98%

Molecular Formula:
C19H18N4O3
Canonical SMILES:
COC1=CC=CC(=C1)C2=CC(=NC(=N2)N)NCC3=CC4=C(C=C3)OCO4
InChI:
InChI=1S/C19H18N4O3/c1-24-14-4-2-3-13(8-14)15-9-18(23-19(20)22-15)21-10-12-5-6-16-17(7-12)26-11-25-16/h2-9H,10-11H2,1H3,(H3,20,21,22,23)
InChIKey:
FABQUVYDAXWUQP-UHFFFAOYSA-N
Solubility:
Soluble to ≥ 30 mg/mL in DMSO.
Appearance:
Solid Powder
Application:
BML-284 may be a useful tool in the study of physiological processes that involve the Wnt pathway.
Storage: 2-8°C
Synonyms:
BML 284; 2-Amino-4-(3,4-(methylenedioxy)benzylamino)-6-(3-methoxyphenyl)pyrimidine; 4-N-(1,3-benzodioxol-5-ylmethyl)-6-(3-methoxyphenyl)pyrimidine-2,4-diamine